1. 1. Preheat the oven to 375°F (190°C).

2. 2. Cook the penne pasta and pasta shells according to package instructions.

3. 3. In a large skillet, melt butter over medium heat. Stir in the all-purpose flour to create a roux.

4. 4. Gradually whisk in the alfredo sauce until smooth.

5. 5. Add cheddar cheese to the sauce, stirring until melted and well combined.

6. 6. In a separate skillet, cook the chicken tenders until fully cooked. Once done, shred or chop the chicken into bite-sized pieces.

7. 7. In a baking dish, layer the cooked pasta, chicken, spinach, corn, and hamburger.

8. 8. Pour the cheesy alfredo sauce over the layered ingredients in the baking dish.

9. 9. In a small bowl, mix bisquick with some cheddar cheese and sprinkle it over the top of the pasta bake.

10. 10. Bake in the preheated oven for 25-30 minutes or until bubbly and golden brown on top.

11. 11. Serve hot and enjoy!